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Alan S Coates Selected Research

Methotrexate (Mexate)

10/2016Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00.
1/2013Trade-offs in quality of life and survival with chemotherapy for advanced breast cancer: mature results of a randomized trial comparing single-agent mitoxantrone with combination cyclophosphamide, methotrexate, 5-fluorouracil and prednisone.
12/2011Capecitabine versus classical cyclophosphamide, methotrexate, and fluorouracil as first-line chemotherapy for advanced breast cancer.
6/2010Classical cyclophosphamide, methotrexate, and fluorouracil chemotherapy is more effective in triple-negative, node-negative breast cancer: results from two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer.
3/2008Chemoendocrine compared with endocrine adjuvant therapies for node-negative breast cancer: predictive value of centrally reviewed expression of estrogen and progesterone receptors--International Breast Cancer Study Group.
1/2007Adjuvant chemotherapy followed by goserelin compared with either modality alone: the impact on amenorrhea, hot flashes, and quality of life in premenopausal patients--the International Breast Cancer Study Group Trial VIII.
10/2005Prognostic value of extracapsular tumor spread for locoregional control in premenopausal patients with node-positive breast cancer treated with classical cyclophosphamide, methotrexate, and fluorouracil: long-term observations from International Breast Cancer Study Group Trial VI.
9/2005Relation between chemotherapy dose, oestrogen receptor expression, and body-mass index.
4/2003Decreased immunoreactivity for p27 protein in patients with early-stage breast carcinoma is correlated with HER-2/neu overexpression and with benefit from one course of perioperative chemotherapy in patients with negative lymph node status: results from International Breast Cancer Study Group Trial V.

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Alan S Coates Research Topics

Disease

85Breast Neoplasms (Breast Cancer)
01/2023 - 03/2003
40Neoplasms (Cancer)
01/2023 - 10/2002
4Hypercholesterolemia
04/2017 - 12/2005
3Arthralgia (Joint Pain)
01/2018 - 02/2007
3Hot Flashes
11/2016 - 01/2007
2Cardiovascular Diseases (Cardiovascular Disease)
02/2021 - 12/2005
2Hypertension (High Blood Pressure)
01/2018 - 12/2007
2Ductal Carcinoma
09/2015 - 09/2009
2Bone Fractures (Bone Fracture)
04/2008 - 02/2007
2Uterine Hemorrhage (Uterine Bleeding)
02/2007 - 12/2005
2Amenorrhea
01/2007 - 03/2006
2Endometrial Neoplasms (Endometrial Cancer)
12/2005 - 12/2004
1Myocardial Ischemia (Ischemic Heart Diseases)
02/2021
1Leukopenia
10/2016
1Vaginal Discharge
10/2016
1Lobular Carcinoma
09/2015
1Osteoporosis
04/2014
1Unilateral Breast Neoplasms
02/2014
1Margins of Excision
02/2014
1Obesity
11/2012
1Infections
12/2011
1Stomatitis
12/2011
1Hand-Foot Syndrome
12/2011
1Febrile Neutropenia
12/2011
1Triple Negative Breast Neoplasms
06/2010
1Necrosis
05/2010
1Fibrosis (Cirrhosis)
05/2010
1Anemia
01/2008
1Heart Failure
02/2007
1Ischemia
02/2007
1Breast Cancer 3
01/2007
1Cataract (Cataracts)
02/2006
1Neuritis (Polyneuritis)
02/2006
1Toxic Optic Neuropathy
02/2006
1Cardiomyopathies (Cardiomyopathy)
01/2006
1Thromboembolism
12/2005
1Noninfiltrating Intraductal Carcinoma (DCIS)
09/2003
1Vaccinia
10/2002

Drug/Important Bio-Agent (IBA)

45TamoxifenFDA LinkGeneric
01/2023 - 09/2003
31Hormones (Hormone)IBA
01/2023 - 12/2005
24Letrozole (Femara)FDA LinkGeneric
02/2021 - 12/2005
23Estrogen ReceptorsIBA
01/2020 - 03/2003
13exemestane (Aromasin)FDA Link
01/2023 - 03/2004
12Aromatase InhibitorsIBA
02/2021 - 12/2005
11Progesterone Receptors (Progesterone Receptor)IBA
01/2023 - 03/2003
11Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2016 - 04/2003
9Methotrexate (Mexate)FDA LinkGeneric
10/2016 - 04/2003
8Fluorouracil (Carac)FDA LinkGeneric
01/2013 - 04/2003
7Estrogens (Estrogen)FDA Link
01/2023 - 09/2007
4ErbB Receptors (EGF Receptor)IBA
01/2023 - 01/2016
4DNA (Deoxyribonucleic Acid)IBA
12/2015 - 06/2010
3Phenobarbital (Luminal)FDA Link
10/2019 - 12/2010
3SteroidsIBA
11/2011 - 12/2005
3Goserelin (Zoladex)FDA Link
03/2008 - 12/2003
2Gonadotropin-Releasing Hormone (GnRH)FDA Link
10/2019 - 12/2003
2Estrogen Receptor alphaIBA
11/2016 - 12/2015
2human ERBB2 proteinIBA
10/2016 - 06/2010
2ProgesteroneFDA LinkGeneric
04/2013 - 09/2007
2Proteins (Proteins, Gene)FDA Link
11/2012 - 04/2003
2Epirubicin (Ellence)FDA LinkGeneric
01/2009 - 01/2006
2Toremifene (Fareston)FDA Link
02/2006 - 12/2004
1Epidermal Growth Factor (EGF)IBA
01/2023
1antineoplaston A10 (A 10)IBA
01/2020
1Triptorelin Pamoate (Trelstar)FDA Link
10/2019
1acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamideFDA Link
10/2019
1CholesterolIBA
04/2017
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
11/2016
1Transaminases (Aminotransferases)IBA
10/2016
1collagen type I trimeric cross-linked peptideIBA
04/2014
1OsteocalcinIBA
04/2014
1Alkaline PhosphataseIBA
04/2014
1liposomal doxorubicin (Doxil)FDA Link
04/2013
11-dodecylpyridoxal (PLD)IBA
04/2013
1Prednisone (Sone)FDA LinkGeneric
01/2013
1Mitoxantrone (Novantrone)FDA LinkGeneric
01/2013
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
03/2012
1P-2 (P 2)IBA
12/2011
1Capecitabine (Xeloda)FDA Link
12/2011
1Androgen Receptors (Androgen Receptor)IBA
12/2010
1Alkylating AgentsIBA
06/2010
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2009
1Trastuzumab (Herceptin)FDA Link
06/2008
1Ki-67 Antigen (Ki 67 Antigen)IBA
02/2008
1Hemoglobins (Hemoglobin)IBA
01/2008
1taxaneIBA
01/2008
1A-factor (Streptomyces)IBA
11/2006
1LigandsIBA
03/2006
1Retinaldehyde (Retinal)IBA
02/2006
1Filgrastim (Neupogen)FDA Link
01/2006
1AnthracyclinesIBA
01/2006
1Cyclin-Dependent Kinase Inhibitor p27IBA
04/2003
1Thymidylate SynthaseIBA
04/2003
1Biomarkers (Surrogate Marker)IBA
03/2003

Therapy/Procedure

48Therapeutics
01/2023 - 09/2003
33Drug Therapy (Chemotherapy)
01/2023 - 04/2003
15Adjuvant Chemotherapy
10/2016 - 04/2003
4Radiotherapy
01/2018 - 05/2007
3Segmental Mastectomy (Lumpectomy)
10/2016 - 06/2008
2Mastectomy (Mammectomy)
02/2014 - 06/2008
1Neoadjuvant Therapy
02/2008